What You Need to Know About Cultiva Live Resin Vaporisers

As more patients turn to inhaled cannabinoid therapies for fast-acting relief, prescribers and pharmacists alike face an increasing need for formats that are not only clinically effective—but also safe, reliable, and environmentally responsible.

Cultiva’s All-in-One Vaporisers are fully recyclable, free from electronic waste, and formulated with unadulterated, full-spectrum live resin for consistent therapeutic outcomes. With no need for a separate 510-thread battery, these devices also eliminate the requirement for a SASB (Single Active Step Battery) approval—streamlining the prescribing process and improving patient access.

Below, we break down what you need to know — from formulation science and hardware performance to patient suitability, bioavailability, and safety.

Designed for Safety:
Reducing Risks in Inhaled Cannabis

Cultiva’s All-in-One devices are engineered to minimise harmful by-products, hardware risks, and additive-related complications.

• No combustion: Vaporisation avoids pyrolysis, eliminating harmful by-products such as benzene, toluene, and polycyclic aromatic hydrocarbons (PAHs) found in combusted cannabis.¹
• No butane or high-heat exposure: Cultiva’s all-in-one device heats extracts at a controlled low temperature, reducing the formation of irritants and preserving terpene structure.
• Hardware integrity: Devices contain no metals or soldered circuit boards, reducing the risk of inhaling heavy metal particulates sometimes found in unregulated or refillable vape products.
• No Harmful Additives: Importantly, Cultiva’s live resin formulations do not contain added flavouring agents such as vitamin E acetate, diacetyl, acetoin, or 2,3-pentanedione. These chemicals have been linked to bronchiolitis obliterans (also known as “popcorn lung”). By excluding these additives, Cultiva’s vaporisers mitigate the risk associated with their inhalation.‍

Environmentally-friendly
All-in One Vaporiser Design

With Australian hospitals producing over 43,000 tonnes of medical waste annually, reducing electronic and chemical waste in prescribing choices can support broader sustainability initiatives in healthcare settings.

Despite being single-patient-use, Cultiva’s All-in-One Vaporisers are fully recyclable and free from hazardous components commonly found in consumer-grade devices:

• No printed circuit board (PCB) or heavy metals
• Removable and recyclable lithium battery
• Biodegradable hemp-based casing
• Natural airflow, no button activation

Live Resin Formulation
for Full-Spectrum Therapy

Cultiva’s All-in-One Vaporisers are formulated with live resin—a high-terpene, full-spectrum extract that more closely mimics the natural chemical profile of the cannabis plant. This supports the entourage effect, which may enhance therapeutic efficacy and reduce the amount needed to achieve symptom relief, compared to more refined or single-compound formats.

Key characteristics of live resin

• Extracted from whole cannabis flower, flash-frozen immediately after harvest to preserve phytochemical integrity
  
• Solvent-extracted using cold hydrocarbon or CO₂ methods to retain minor cannabinoids and volatile terpenes
  
• Rich in monoterpenes (e.g., myrcene, limonene, ocimene), cannabinoids, flavonoids, and native plant lipids
  
• Inhaled format enables rapid onset—ideal for patients with breakthrough symptoms such as pain, anxiety, or nausea

Built for Device Performance

Live resin doesn’t just enhance the clinical effect—it also performs better within vaporiser hardware compared with rosin, distillates and oils, making it particularly suited to single-patient-use, draw-activated devices like Cultiva’s All-in-One vaporisers.

By avoiding the viscosity issues and separation problems common with distillates and oils, live resin ensures reliable device function and cleaner, smoother delivery—ideal for both first-time and experienced patients.

• Lower viscosity liquid flows more easily through the wick and coil system, reducing clogging and ineffective inhalations.
• Vaporises evenly at lower temperatures. This controlled heating preserves the integrity of cannabinoids and terpenes, helping to maintain therapeutic effects while minimising thermal degradation. For clinicians, this means greater confidence in consistent dosing, fewer irritants, and improved tolerability—especially for patients with respiratory sensitivity.
• Vaporises live resin evenly at lower temperatures, delivering a consistent vapour output with each use. This supports smoother, more predictable inhalation and reduces variability in cannabinoid delivery—enhancing dose reliability for both clinicians and patients.
  

Fast Relief:
‍Clinical Considerations for Vaporised Cannabinoids

Inhalation provides one of the most efficient delivery routes for cannabinoids with high bioavailability. After inhalation, cannabinoids bypass first-pass hepatic metabolism, entering systemic circulation via the alveolar-capillary network in the lungs. Reported pulmonary bioavailability of THC ranges from 10–35%, depending on breath-hold duration, vaporisation temperature, and individual lung function.²

Onset and Titration

• Onset of action: Typically within 1–5 minutes, making inhaled formats suitable for acute symptom relief (e.g. breakthrough pain, nausea, panic). This rapid feedback allows patients to self-titrate more accurately in real-time compared to oral products, where peak plasma concentrations can take 30–90 minutes to develop. Peak effects usually occur within 10–30 minutes and begin to decline after 2–3 hours.³

Duration of Action

• The therapeutic window for inhaled cannabinoids is generally 2–4 hours, shorter than oral forms.
• For patients managing chronic conditions, vaporisers are best used in combination with longer-acting products (e.g. Blüm Pastilles) to provide both rapid symptom relief and consistent baseline coverage. This mirrors standard approaches in pain and anxiety management, where both short- and long-acting formulations are often prescribed together.